Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817861 | 0.84 | ALDH1A1 (0.44) | L3MBTL1ARSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7371681 | 0.78 | ALDH1A1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1LMNAGALR2 | |
| SCHEMBL7119418 | 0.75 | AR (0.49) | L3MBTL1ARSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16529634 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1LMNAGALR2MITF | |
| SCHEMBL10737968 | 0.73 | MEN1 (0.57) | L3MBTL1HSP90AA1MAPTKMT2AMEN1 | |
| SCHEMBL1523174 | 0.73 | ALDH1A1 (0.67) | L3MBTL1SMN1; SMN2ALDH1A1LMNAGALR2 | |
| SCHEMBL6422578 | 0.72 | KMT2A (0.65) | SMN1; SMN2ALDH1A1LMNAGALR2MITF | |
| SCHEMBL2126420 | 0.72 | CA12 (0.62) | SMN1; SMN2ALDH1A1LMNAGALR2MITF | |
| SCHEMBL6750268 | 0.72 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1LMNAGALR2MITF | |
| Hydrochloric Acid SCHEMBL11776974 | 0.71 | TSHR (0.57) | SMN1; SMN2ALDH1A1LMNAGALR2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |