Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MITF | O75030 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GALR2 | O43603 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14114749 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MITFLMNAPOLB | |
| SCHEMBL7723906 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL426382 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1POLBHPGDMAPT | |
| SCHEMBL16529634 | 0.86 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1MITFLMNAPOLB | |
| SCHEMBL5925545 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL6422578 | 0.85 | KMT2A (0.65) | SMN1; SMN2ALDH1A1MITFLMNAPOLB | |
| SCHEMBL2126420 | 0.85 | CA12 (0.62) | SMN1; SMN2ALDH1A1MITFLMNAPOLB | |
| SCHEMBL10426612 | 0.84 | PKM (0.51) | SMN1; SMN2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL9420561 | 0.84 | CES2 (0.50) | SMN1; SMN2ALDH1A1POLBHPGDMAPT | |
| SCHEMBL3092769 | 0.84 | MAPT (0.55) | SMN1; SMN2ALDH1A1MITFLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713454-A | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2020-01-21 | — | — | CN | claimed |
| US-20040142946-A1 | Modified nucleosides and nucleotides and use thereof | CHATTOPADHYAYA JYOTI (SE) | 2004-07-22 | — | — | US | claimed |
| EP-1332150-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF | Chattopadhyaya, Jyoti (SE) | 2003-08-06 | — | — | EP | claimed |
| WO-2002038578-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF | CHATTOPADHYAYA JYOTI (SE) | 2002-05-16 | — | — | WO | claimed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | claimed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| CN-117776942-A | Method for preparing diaminobenzoic acid based on dinitrobenzoic acid | 清源创新实验室 | 2024-03-29 | — | — | CN | disclosed |
| US-20230226228-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-07-20 | — | — | US | disclosed |
| US-20230226228-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-07-20 | — | — | US | disclosed |
| CN-110713454-B | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2022-12-09 | — | — | CN | disclosed |
| WO-2021226076-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-11-11 | — | — | WO | disclosed |
| CN-110713454-A | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2020-01-21 | — | — | CN | disclosed |
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0272742-B1 | METHOD FOR PREPARATION OF MERCAPTOBENZOATES | STAUFFER AGRICULTURAL CHEMICALS COMPANY, INC. (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0272742-A1 | Method for preparation of mercaptobenzoates | STAUFFER AGRICULTURAL CHEMICALS COMPANY, INC. (US) | 1988-06-29 | — | — | EP | disclosed |
| US-4692545-A | Method for preparation of mercaptobenzoates | STAUFFER CHEMICAL COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142946-A1 | Modified nucleosides and nucleotides and use thereof | RNASEH1, RNASEL, NSUN2 | SMN1; SMN2 1974/4885ALDH1A1 4684/4885MITF 2324/4885 |
| US-20230226228-A1 | POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION AND METHOD FOR DETECTION OF BACTERIAL INFECTION | TLR5, SLC10A2, FNTB | SMN1; SMN2 3077/4885ALDH1A1 3223/4885MITF 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.