Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710872 | 0.77 | MAOB (0.50) | MAOBEPHX1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL5304483 | 0.76 | DPP4 (0.44) | DPP4F2TAAR1HTR2A | |
| SCHEMBL794180 | 0.74 | MAOB (0.46) | MAOBTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL9226100 | 0.72 | MAOB (0.44) | MAOBEPHX1TAAR1SLC6A2MAOA | |
| SCHEMBL17286844 | 0.72 | DPP4 (0.50) | DPP4F2TAAR1HTR2A | |
| SCHEMBL11967590 | 0.71 | MAOB (0.43) | MAOBSIGMAR1MAPK1 | |
| SCHEMBL4702113 | 0.71 | MAOB (0.43) | MAOBEPHX1TAAR1SLC6A2MAOA | |
| SCHEMBL11498274 | 0.71 | MAOB (0.43) | MAOBEPHX1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL1298830 | 0.71 | MAOB (0.43) | MAOBEPHX1TAAR1SLC6A2MAOA | |
| SCHEMBL14246706 | 0.71 | HRH1 (0.43) | MAOBEPHX1TAAR1SLC6A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9165384-A | — | — | None | — | — | JP | disclosed |
| JP-H09165384-A | NEW DIPHENYLPROPYLPIPERAZINE DERIVATIVE | SANTEN PHARMACEUT CO LTD | 1997-06-24 | — | — | JP | disclosed |