Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554181 | 0.82 | MAOA (0.44) | MAOBSIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL1289345 | 0.79 | MAOB (0.52) | MAOBTRPA1SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL10348037 | 0.79 | MAOB (0.54) | MAOBTRPA1SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL3624305 | 0.79 | TRPA1 (0.43) | TRPA1SIGMAR1TAAR1SLC6A2SLC6A4 | |
| Phenylacetaldehyde SCHEMBL10627457 | 0.78 | TAAR1 (0.42) | MAOBTRPA1SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL8710872 | 0.77 | MAOB (0.50) | MAOBSIGMAR1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL4155331 | 0.76 | MAOB (0.48) | MAOBTRPA1SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL8174260 | 0.76 | MAOB (0.48) | MAOBTRPA1SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL3295095 | 0.76 | MAOB (0.48) | MAOBTRPA1SIGMAR1TAAR1SLC6A2 | |
| SCHEMBL9205893 | 0.76 | TAAR1 (0.52) | TRPA1TAAR1ADRA2CHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103665018-B | Silane compound and preparation method thereof | 中国石油化工股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| WO-2001052868-A9 | COMBINATIONS FOR TREATING NEOPLASMS | YU BAOFA (US) | 2003-01-16 | — | — | WO | claimed |
| US-5127935-A | Halogen, phenyl and heterocycle substituents, agricultural use | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-07-07 | — | — | US | claimed |
| EP-2139835-B1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2352719-B1 | METHOD FOR PRODUCING N,N-SUBSTITUTED-3-AMINOPROPAN-1-OLS | BASF SE (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-3023418-A1 | METHOD FOR MANUFACTURING CYCLIC CARBONATE | National Institute of Advanced Industrial Science and Technology (JP) | 2016-05-25 | — | — | EP | disclosed |
| EP-2616429-B1 | METHOD FOR PRODUCING AROMATIC AMINES | BASF SE (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-20130281680-A1 | PROCESS FOR PRODUCING COELENTERAMIDE OR AN ANALOG THEREOF | JNC CORP (JP) | 2013-10-24 | — | — | US | disclosed |
| EP-2616429-A1 | METHOD FOR PRODUCING AROMATIC AMINES | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| EP-2279164-B1 | METHOD FOR PRODUCING N,N-SUBSTITUTED-1,3-PROPANDIAMINES | BASF SE (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2012034933-A1 | METHOD FOR PRODUCING AROMATIC AMINES | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| WO-2006040096-A1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-04-20 | — | — | WO | disclosed |
| EP-1537071-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 2-AMINO-,2-CHLORO-,2-HYDROXY- OR 2-ALKOXY-1-ALCOHOLS | BASF AG (DE) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005077870-A1 | HYDROGENATION METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS OR CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | WO | disclosed |
| WO-2005077871-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS OR CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-25 | — | — | WO | disclosed |
| EP-1537071-A1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 2-AMINO-,2-CHLORO-,2-HYDROXY OR 2-ALKOXY-1-ALCOHOLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022522-A1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE 2-AMINO-,2-CHLORO-,2-HYDROXY OR 2-ALKOXY-1-ALCOHOLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-18 | — | — | WO | disclosed |
| US-6511997-B1 | For treatment of a disease associated with tumor necrosis factor alpha, interleukin 1, interleukin 6 or cyclooxygenase II; such as irritable bowel disease | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| WO-2001052868-A9 | COMBINATIONS FOR TREATING NEOPLASMS | YU BAOFA (US) | 2003-01-16 | — | — | WO | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281680-A1 | PROCESS FOR PRODUCING COELENTERAMIDE OR AN ANALOG THEREOF | HNMT, DIMT1, SI | MAOB 463/4885TRPA1 2660/4885SIGMAR1 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.