Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817755 | 0.79 | NISCH (0.35) | NISCHSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL9291204 | 0.76 | MAOA (0.36) | NISCHSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL11572938 | 0.75 | GAA (0.33) | — | |
| SCHEMBL5364558 | 0.73 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL2200816 | 0.73 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2011593 | 0.73 | NISCH (0.34) | NISCHSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7993381 | 0.72 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2880193 | 0.71 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9152285 | 0.70 | NISCH (0.33) | NISCHSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL2204376 | 0.70 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046549-A1 | ANTI-NEURODEGENERATIVELY EFFECTIVE XANTHENE DERIVATIVES | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | claimed |
| EP-0354553-A2 | Aryl cyanoguanidines: potassium channel activators and method of making same | E.R. SQUIBB & SONS, INC. (US) | 1990-02-14 | — | — | EP | claimed |