Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | IDE | P14735 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | CA12 | O43570 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | CA9 | Q16790 | 5/20 | 0.58 |
| ▸ | HLCS | P50747 | 4/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810465 | 0.98 | TDP1 (0.74) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13110899 | 0.87 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13185305 | 0.87 | FOLH1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL9412852 | 0.87 | TDP1 (0.74) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL9174298 | 0.86 | TDP1 (0.79) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL12606268 | 0.86 | TDP1 (0.79) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL18268949 | 0.86 | TDP1 (0.79) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL25417015 | 0.85 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL565479 | 0.85 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL16913029 | 0.85 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997035194-A2 | ENANTIOMERIC SCREENING PROCESS, AND COMPOSITIONS THEREFOR | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1997-09-25 | — | — | WO | disclosed |