SCHEMBL1810465

SCHEMBL1810465

O=C(O)CNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 5/20 0.74
▸ MEN1 O00255 1/20 0.74
▸ ABL1 P00519 1/20 0.74
▸ LMNA P02545 1/20 0.74
▸ PKM P14618 1/20 0.74
▸ IDE P14735 1/20 0.74
▸ MAPK1 P28482 1/20 0.74
▸ KMT2A Q03164 1/20 0.74
▸ RIN1 Q13671 1/20 0.74
▸ L3MBTL1 Q9Y468 1/20 0.74
▸ CA12 O43570 6/20 0.60
▸ CA1 P00915 6/20 0.60
▸ CA2 P00918 6/20 0.60
▸ CA9 Q16790 6/20 0.60
▸ HLCS P50747 4/20 0.59
▸ FOLH1 Q04609 2/20 0.54
▸ F2 P00734 1/20 0.53
▸ PRSS1 P07477 1/20 0.53
▸ PRSS2 P07478 1/20 0.53
▸ PRSS3 P35030 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8819529 0.98 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
SCHEMBL13110899 0.89 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
SCHEMBL13185305 0.89 FOLH1 (0.63) TDP1MEN1ABL1LMNAPKM
SCHEMBL9412852 0.89 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
SCHEMBL9174298 0.88 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
SCHEMBL12606268 0.88 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
SCHEMBL18268949 0.88 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
SCHEMBL25417015 0.87 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL10171661 0.87 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL16913029 0.87 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896762-B Liquid phase synthesis method of biotin tripeptide-1 浙江湃肽生物有限公司深圳分公司 2022-03-29 — — CN claimed
CN-119470877-A Biotinylation modified amino acid probe, preparation method and application thereof, and method and application for identifying amino acid binding protein 同济大学 2025-02-18 — — CN disclosed
US-20230285464-A1 NOVEL CELLULAR RECEPTORS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2023-09-14 — — US disclosed
US-11672828-B2 Cellular receptors and uses thereof TRUSTEES OF BOSTON UNIVERSITY (US) 2023-06-13 — — US disclosed
CN-113896762-B Liquid phase synthesis method of biotin tripeptide-1 浙江湃肽生物有限公司深圳分公司 2022-03-29 — — CN disclosed
CN-113896762-B Liquid phase synthesis method of biotin tripeptide-1 浙江湃肽生物有限公司深圳分公司 2022-03-29 — — CN disclosed
WO-2021163018-A1 NOVEL CELLULAR RECEPTORS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2021-08-19 — — WO disclosed
US-20210244764-A1 NOVEL CELLULAR RECEPTORS AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2021-08-12 — — US disclosed
EP-2755667-A2 METHOD FOR ENHANCING THE GROWTH AND FULLNESS OF HAIR Avon Products, Inc. (US) 2014-07-23 — — EP disclosed
WO-2013039597-A2 METHOD FOR ENHANCING THE GROWTH AND FULLNESS OF HAIR AVON PRODUCTS, INC. (US) 2013-03-21 — — WO disclosed
US-20030228254-A1 Diagnosis of cardiovascular disorders AMERSHAM HEALTH AS (NO) 2003-12-11 — — US disclosed
US-6524552-B2 Imaging cardiovascular disorders GE HEALTHCARE AS (NO) 2003-02-25 — — US disclosed
US-20010016587-A1 Contrast agents NYCOMED IMAGING AS 2001-08-23 — — US disclosed
EP-1007101-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS Marsden, John Christopher (GB) 2000-06-14 — — EP disclosed
EP-0973552-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS Marsden, John Christopher (GB) 2000-01-26 — — EP disclosed
EP-0971747-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 2000-01-19 — — EP disclosed
CN-1238700-A Improvements in or relating to diagnostic and/or therapeutic agents NYCOMED IMAGING AS (NO) 1999-12-15 — — CN disclosed
WO-1998018496-A2 CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1998-05-07 — — WO disclosed
WO-1998018500-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS MARSDEN, JOHN, CHRISTOPHER (GB) 1998-05-07 — — WO disclosed
WO-1998018501-A2 IMPROVEMENTS IN OR RELATING TO DIAGNOSTIC/THERAPEUTIC AGENTS MARSDEN, JOHN, CHRISTOPHER (GB) 1998-05-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210244764-A1 NOVEL CELLULAR RECEPTORS AND USES THEREOF SRPRA, CACYBP, SRPRB TDP1 3400/4885MEN1 4246/4885ABL1 4564/4885
US-11672828-B2 Cellular receptors and uses thereof SRPRA, NPBWR1, BCAP31 TDP1 3462/4885MEN1 3868/4885ABL1 4348/4885
US-20030228254-A1 Diagnosis of cardiovascular disorders AGTR1, AGTR2, AGT TDP1 4049/4885MEN1 693/4885ABL1 1544/4885
US-20010016587-A1 Contrast agents AGTR1, AGTR2, VIPR1 TDP1 4074/4885MEN1 386/4885ABL1 1453/4885
US-20230285464-A1 NOVEL CELLULAR RECEPTORS AND USES THEREOF SRPRA, CACYBP, SRPRB TDP1 3400/4885MEN1 4246/4885ABL1 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback