Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.43 |
| ▸ | PGK2 | P07205 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23703226 | 0.84 | HTT (0.39) | PGK1PGK2HTTRAPGEF4POLB | |
| SCHEMBL17743470 | 0.83 | HTT (0.38) | HTTRAPGEF4POLBMEN1ALDH1A1 | |
| SCHEMBL30236538 | 0.81 | RAPGEF4 (0.44) | HTTRAPGEF4POLBMEN1ALDH1A1 | |
| SCHEMBL1607815 | 0.81 | RAPGEF4 (0.44) | HTTRAPGEF4POLBMEN1ALDH1A1 | |
| SCHEMBL19209749 | 0.81 | EGFR (0.39) | HTTRAPGEF4ALDH1A1KDM4EMAPT | |
| SCHEMBL3339137 | 0.80 | HSD17B10 (0.39) | RAPGEF4POLBMEN1ALDH1A1KMT2A | |
| Water SCHEMBL27145442 | 0.80 | RAPGEF4 (0.43) | HTTRAPGEF4POLBMEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28142626 | 0.79 | HSD17B10 (0.38) | RAPGEF4POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL30716894 | 0.78 | AMY1A (0.44) | HTTRAPGEF4POLBMEN1ALDH1A1 | |
| SCHEMBL1180196 | 0.78 | GAA (0.41) | RAPGEF4POLBMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997036909-A1 | WITTIG REAGENTS AND METHOD FOR PREPARING α,β-UNSATURATED PHOSPHONATES | MEDICHEM RESEARCH, INC. (US) | 1997-10-09 | — | — | WO | disclosed |