SCHEMBL8819851

SCHEMBL8819851

NC(=O)C(Br)CC(=O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
SLC15A1 P46059 2/20 0.51
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CDC25B P30305 1/20 0.46
ABCB1 P08183 1/20 0.44
LMNA P02545 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
TSHR P16473 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10068394 0.87 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
SCHEMBL7413100 0.83 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
SCHEMBL14194794 0.82 SLC15A1 (0.58) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
SCHEMBL7348049 0.82 SLC15A1 (0.59) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
Hydrochloric Acid SCHEMBL29401501 0.81 SLC15A1 (0.58) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
SCHEMBL9284609 0.80 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
SCHEMBL10068401 0.79 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
Hydrochloric Acid SCHEMBL19511476 0.78 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
Hydrochloric Acid SCHEMBL27518479 0.78 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2
SCHEMBL6546883 0.78 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997033625-A2 WATER-SOLUBLE LIPOPHILIC CONTRAST AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-09-18 WO disclosed