SCHEMBL8819899

SCHEMBL8819899

CCCCCCCCc1ccc(-c2ccc(C(=O)OCC(O)CCCCCC)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.57
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ALDH1A1 P00352 1/20 0.57
RARA P10276 1/20 0.57
MAPT P10636 1/20 0.57
MTOR P42345 1/20 0.57
THRA P10827 5/20 0.49
THRB P10828 5/20 0.49
S1PR1 P21453 1/20 0.48
PLA2G1B P04054 5/20 0.47
ATG4B Q9Y4P1 5/20 0.47
CYP1A2 P05177 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13842072 0.90 RARB (0.57) RARBMEN1KMT2AALDH1A1RARA
SCHEMBL8062468 0.88 ALDH1A1 (0.53) ALDH1A1MAPTCYP1A2
SCHEMBL8062472 0.88 ALDH1A1 (0.53) ALDH1A1MAPTCYP1A2
SCHEMBL31359393 0.83 ESR1 (0.59) MEN1KMT2AALDH1A1MAPTCYP1A2
SCHEMBL11043289 0.83 RARB (0.68) RARBMEN1KMT2AALDH1A1RARA
SCHEMBL4182052 0.83 RARB (0.68) RARBMEN1KMT2AALDH1A1RARA
SCHEMBL23926216 0.82 ALDH1A1 (0.57) ALDH1A1MAPTCYP1A2
SCHEMBL11225321 0.82 MAPT (0.59) RARBMEN1KMT2AALDH1A1RARA
SCHEMBL6895497 0.81 THRA (0.54) RARBMEN1KMT2AALDH1A1RARA
SCHEMBL6894199 0.81 THRA (0.54) RARBMEN1KMT2AALDH1A1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9291283-A None JP disclosed
JP-H09291283-A IMPROVER OF LIQUID CRYSTAL CHARACTERISTIC AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME SHOWA SHELL SEKIYU KK 1997-11-11 JP disclosed