Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | ABL2 | P42684 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820717 | 0.86 | PI4KB (0.55) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8819987 | 0.80 | SRC (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8820760 | 0.80 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8820773 | 0.75 | PIK3CD (0.41) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL8819985 | 0.74 | NPC1 (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8344172 | 0.67 | GSK3B (0.58) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8819980 | 0.66 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8820514 | 0.66 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8819623 | 0.66 | SRC (0.61) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL7700541 | 0.63 | MAPT (0.48) | ALDH1A1MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | disclosed |