Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KIF5B | P33176 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294631 | 0.79 | ALDH1A1 (0.46) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8326548 | 0.78 | CA12 (0.50) | ALDH1A1TSHRRETKIF5BKDR | |
| SCHEMBL7302858 | 0.77 | PKM (0.45) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4427054 | 0.76 | EDNRB (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30053231 | 0.74 | SMN1; SMN2 (0.72) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13167638 | 0.74 | SMN1; SMN2 (0.72) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29929943 | 0.74 | SMN1; SMN2 (0.72) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1061713 | 0.74 | SMN1; SMN2 (0.72) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7979230 | 0.74 | MAPT (0.58) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL12826224 | 0.74 | ALDH1A1 (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |