Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 5/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | ABL2 | P42684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819676 | 0.88 | PI4KA (0.47) | NPC1RAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL8819945 | 0.85 | MAPT (0.36) | NPC1RAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL8819716 | 0.85 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8819987 | 0.80 | SRC (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL8819661 | 0.78 | SRC (0.38) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL8819680 | 0.74 | SRC (0.36) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL8819904 | 0.74 | PI4KA (0.44) | NPC1RAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL8820521 | 0.73 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8820760 | 0.73 | PI4KA (0.41) | NPC1RAB9API4KAPI4K2BPI4K2A | |
| SCHEMBL8819471 | 0.73 | PI4KA (0.46) | NPC1RAB9API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | disclosed |