Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.83 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8820000 | 1.00 | ADORA3 (0.83) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL8820459 | 0.91 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL8818565 | 0.91 | ADORA3 (0.85) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL8817947 | 0.91 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL8818548 | 0.91 | ADORA3 (0.85) | ADORA3ADORA2AADORA1ADORA2BMEN1 | |
| SCHEMBL14906327 | 0.88 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL6809456 | 0.88 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL6809452 | 0.88 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL18526554 | 0.86 | ADORA3 (0.80) | ADORA3ADORA2AADORA1ADORA2BNT5E | |
| SCHEMBL4451649 | 0.84 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033590-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997033591-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |