Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26999697 | 1.00 | BCHE (0.52) | BCHEHDAC8HDAC6KDM2BHSD11B1 | |
| SCHEMBL24777711 | 0.86 | BCHE (0.68) | BCHEKDM2BHSD11B1CCR2KCNH2 | |
| SCHEMBL3461210 | 0.85 | BCHE (0.51) | BCHEKDM2BHSD11B1CCR2KCNH2 | |
| SCHEMBL441659 | 0.85 | BCHE (0.69) | BCHEKDM2BHSD11B1CCR2KCNH2 | |
| SCHEMBL21486158 | 0.83 | TSHR (0.57) | BCHEKDM2BHSD11B1CCR2KCNH2 | |
| SCHEMBL9396978 | 0.83 | HDAC8 (0.47) | BCHEHDAC8HDAC6KDM2BKDM4E | |
| Hydrochloric Acid SCHEMBL9397165 | 0.81 | HDAC8 (0.46) | BCHEHDAC8HDAC6KDM2BKDM4E | |
| SCHEMBL740141 | 0.80 | SMN1; SMN2 (0.54) | BCHEKDM2BHSD11B1SMN1; SMN2TSHR | |
| SCHEMBL771607 | 0.80 | SMN1; SMN2 (0.54) | BCHEKDM2BHSD11B1SMN1; SMN2TSHR | |
| SCHEMBL13149470 | 0.80 | BCHE (0.47) | BCHEKDM2BHSD11B1CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049403-A1 | USE OF NIPECOTIC ACID OR GUVACINE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF POSTISCHEMIC NEURODEGENERATIVE DISORDERS | UNIVERSITY COLLEGE DUBLIN (US) | 1997-12-31 | — | — | WO | disclosed |