Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15656816 | 0.89 | GPR119 (0.44) | GPR119USP30FPR2ALDH1A1KRAS | |
| SCHEMBL7350588 | 0.86 | GPR119 (0.49) | GPR119USP30FPR2BACE1ALDH1A1 | |
| SCHEMBL8818127 | 0.85 | GSK3B (0.37) | KRASCYP3A4HTT | |
| SCHEMBL7344659 | 0.84 | GPR119 (0.53) | GPR119USP30FPR2CYP3A4NR3C1 | |
| SCHEMBL8818888 | 0.84 | GPR119 (0.44) | GPR119USP30FPR2NSD2 | |
| SCHEMBL31583380 | 0.84 | GPR119 (0.44) | GPR119USP30FPR2BACE1KRAS | |
| SCHEMBL29121705 | 0.81 | BTK (0.45) | GPR119USP30FPR2KRAS | |
| SCHEMBL30676388 | 0.81 | BTK (0.45) | GPR119USP30FPR2KRAS | |
| SCHEMBL29121565 | 0.81 | BTK (0.45) | GPR119USP30FPR2KRAS | |
| SCHEMBL30676570 | 0.81 | BTK (0.45) | GPR119USP30FPR2KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049698-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOTIC DISORDERS | GLAXO GROUP LIMITED (GB) | 1997-12-31 | — | — | WO | disclosed |