Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819471 | 0.87 | PI4KA (0.46) | MAPTKDM4EALDH1A1HTTLMNA | |
| SCHEMBL8819985 | 0.85 | NPC1 (0.39) | MAPTALDH1A1HTTFFAR2PI4KA | |
| SCHEMBL8820698 | 0.76 | LIMK1 (0.37) | FFAR2ABL1EGFRSRCKDR | |
| SCHEMBL8819716 | 0.76 | PI4KA (0.48) | ALDH1A1HTTPI4KAPI4K2BPI4K2A | |
| SCHEMBL8819948 | 0.74 | PI4KA (0.36) | MAPTKDM4EALDH1A1HTTLMNA | |
| SCHEMBL8819676 | 0.73 | PI4KA (0.47) | ALDH1A1HTTFFAR2PI4KAPI4K2B | |
| SCHEMBL8819671 | 0.71 | EGFR (0.42) | KDM4EALDH1A1FFAR2PI4KAPI4K2B | |
| SCHEMBL8819680 | 0.69 | SRC (0.36) | KDM4EPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8819987 | 0.68 | SRC (0.50) | MAPTKDM4EALDH1A1HTTLMNA | |
| SCHEMBL8819661 | 0.66 | SRC (0.38) | KDM4EFFAR2PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049706-A1 | SUBSTITUTED 7-AMINO-PYRROLO[3,2-d]PYRIMIDINES AND THE USE THEREOF | NOVARTIS AG (CH) | 1997-12-31 | — | — | WO | disclosed |