Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325480 | 0.83 | HTR6 (0.46) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL7385171 | 0.81 | EPHX2 (0.46) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL7497164 | 0.81 | EPHX2 (0.46) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL7497168 | 0.81 | EPHX2 (0.46) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL6958925 | 0.80 | ALDH1A1 (0.47) | MAPTMEN1KMT2AGAAGPR119 | |
| SCHEMBL25679165 | 0.79 | MAPT (0.45) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL20601907 | 0.79 | MAPT (0.45) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL31585552 | 0.79 | MAPT (0.45) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL30456238 | 0.77 | MAPT (0.41) | MAPTTP53LMNAMEN1KMT2A | |
| SCHEMBL31585998 | 0.74 | MAPT (0.56) | MAPTTP53LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9168396-A | — | — | None | — | — | JP | disclosed |
| JP-H09168396-A | PRODUCTION OF OPTICALLY ACTIVE 5-HYDROXY-2,3,4,5-TETRAHYDRO-1H-BENZAZEPINE DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1997-06-30 | — | — | JP | disclosed |