SCHEMBL882115

SCHEMBL882115

N#Cc1ccnc(N)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900681 0.77
SCHEMBL2238411 0.74 KMO (0.44)
SCHEMBL15133166 0.74
SCHEMBL20391030 0.73
SCHEMBL1186629 0.73
SCHEMBL10863909 0.73
SCHEMBL17621795 0.73
SCHEMBL15122785 0.73
SCHEMBL17185598 0.73
SCHEMBL15778605 0.72 CTSK (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016135286-A1 METHOD FOR STIMULATING DENDRITIC CELLS (DCS) ACTIVARTIS BIOTECH GMBH (AT) 2016-09-01 WO claimed
EP-4651944-A1 INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF Ventus Therapeutics U.S., Inc. (US) 2025-11-26 EP disclosed
EP-4585596-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF Shanghai Yingli Pharmaceutical Co., Ltd (CN) 2025-07-16 EP disclosed
WO-2024233767-A1 INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2024-11-14 WO disclosed
US-20240158408-A1 Nitrogen-Containing Heterocyclic Compound, Pharmaceutical Compositions thereof and Use thereof 280 BIO, INC. (US) 2024-05-16 US disclosed
WO-2023137353-A1 15-PGDH INHIBITORS VENTYX BIOSCIENCES, INC. (US) 2023-07-20 WO disclosed
WO-2023137353-A1 15-PGDH INHIBITORS VENTYX BIOSCIENCES, INC. (US) 2023-07-20 WO disclosed
WO-2021212039-A1 INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF Pardes Biosciences, Inc. (US) 2021-10-21 WO disclosed
EP-3452465-B1 SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES GENOSCIENCE PHARMA (FR) 2020-11-04 EP disclosed
US-10577362-B2 Substituted 2, 4-diamino-quinoline derivatives for use in the treatment of proliferative diseases GENOSCIENCE PHARMA (FR) 2020-03-03 US disclosed
US-20120245162-A1 OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-09-27 US disclosed
EP-2081919-B1 TETRAHYDROFURO [3, 2-B]PYRR0L-3-0NE INTERMEDIATES AMURA THERAPEUTICS LTD (GB) 2012-05-23 EP disclosed
WO-2012040137-A1 OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-03-29 WO disclosed
US-8039641-B2 Tetrahydrofuro[3,2-b] pyrrol-3-one intermediates AMURA THERAPEUTICS LIMITED (GB) 2011-10-18 US disclosed
US-20090192322-A1 Tetrahydrofuro[3,2-b] pyrrol-3-one intermediates AMURA THERAPEUTICS LIMITED (GB) 2009-07-30 US disclosed
US-20090005575-A1 Preparation of diazapentalene derivatives via epoxydation of dihydropyrroles AMURA THERAPEUTICS LTD. (GB) 2009-01-01 US disclosed
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed
US-4524124-A PHOTOSTABLE CYAN IMAGE DYES FOR DYE DIFFUSION TRANSFER AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
US-4110453-A N-(2-PYRIMIDINYL)1H-(OR 2H)TETRAZOLE-5-CARBOXAMIDE DERIVATIVES FOR THE PREVENTION OF IMMEDIATE TYPE HYPERSENSITIVITY REACTIONS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-08-29 US disclosed