Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8110360 | 0.82 | CHRM3 (0.66) | MAPTMEN1KMT2AGNAI3CHRM2 | |
| SCHEMBL6941984 | 0.82 | CHRM3 (0.66) | MAPTMEN1KMT2AGNAI3CHRM2 | |
| SCHEMBL807236 | 0.82 | KDM4E (0.68) | LMNAKDM4EMAPTALOX15HTT | |
| Hydrochloric Acid SCHEMBL11539098 | 0.81 | CHRM3 (0.64) | MAPTMEN1KMT2AGNAI3CHRM2 | |
| SCHEMBL20460271 | 0.80 | KDM4E (0.65) | LMNAKDM4EMAPTALOX15HTT | |
| SCHEMBL24162993 | 0.78 | KDM4E (0.66) | LMNAKDM4EMAPTALOX15HTT | |
| SCHEMBL2226923 | 0.76 | ALDH1A1 (0.62) | LMNAKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6496988 | 0.76 | CXCR4 (0.58) | MEN1KMT2AGNAI3CHRM2CHRM4 | |
| SCHEMBL20460351 | 0.76 | ALDH1A1 (0.72) | LMNAKDM4EMAPTALOX15HTT | |
| SCHEMBL4300937 | 0.76 | KDR (0.50) | KDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997045119-A1 | USE OF SUBSTANCE P ANTAGONISTS FOR TREATING SOCIAL PHOBIA | NOVARTIS AG (CH) | 1997-12-04 | — | — | WO | disclosed |