SCHEMBL8822129 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CALML3	P27482	7/20	0.47

▸	MAOB	P27338	8/20	0.44

▸	MAOA	P21397	7/20	0.43

▸	CYP2C19	P33261	2/20	0.41

▸	CYP3A4	P08684	1/20	0.41

▸	LMNA	P02545	1/20	0.41

▸	PTGS1	P23219	1/20	0.41

▸	SDHA	P31040	1/20	0.41

▸	CYP2C9	P11712	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8822067	0.90	CALML3 (0.56)	CALML3MAOBMAOACYP2C19CYP3A4
SCHEMBL5657145	0.86	MAOB (0.48)	CALML3MAOBMAOALMNAPTGS1
SCHEMBL4018839	0.86	MAOB (0.48)	CALML3MAOBMAOALMNAPTGS1
SCHEMBL13939851	0.84	MAOB (0.46)	CALML3MAOBMAOACYP2C19CYP3A4
SCHEMBL3755981	0.81	MAOB (0.43)	CALML3MAOBMAOALMNAPTGS1
SCHEMBL7659799	0.81	MAOB (0.43)	CALML3MAOBMAOALMNAPTGS1
SCHEMBL3755980	0.81	MAOB (0.43)	CALML3MAOBMAOALMNAPTGS1
SCHEMBL5235589	0.81	CALML3 (0.56)	CALML3MAOBMAOACYP2C19CYP3A4
SCHEMBL13081072	0.81	CALML3 (0.56)	CALML3MAOBMAOACYP2C19CYP3A4
SCHEMBL5834576	0.81	CALML3 (0.56)	CALML3MAOBMAOACYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1997031917-A9	SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS	—	1997-10-30	—	—	WO	disclosed
WO-1997031917-A1	SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS	ZENECA LIMITED (GB)	1997-09-04	—	—	WO	disclosed