Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28737659 | 0.79 | TDP1 (0.35) | TDP1 | |
| SCHEMBL8245161 | 0.77 | PGD (0.37) | PGDSLC22A6CACNA2D1ADRA1ACACNB3 | |
| SCHEMBL2873742 | 0.77 | PGD (0.37) | PGDSLC22A6CACNA2D1ADRA1ACACNB3 | |
| SCHEMBL7756027 | 0.77 | TSHR (0.32) | TDP1TSHR | |
| SCHEMBL2027984 | 0.77 | TDP1 (0.36) | PGDSLC22A6ADRA1ATDP1SMN1; SMN2 | |
| SCHEMBL10950172 | 0.76 | PGD (0.35) | PGDTDP1SMN1; SMN2 | |
| SCHEMBL5881679 | 0.76 | GAA (0.40) | TDP1CHRM1TSHRALDH1A1HSD17B10 | |
| SCHEMBL28745113 | 0.74 | CYP1A2 (0.41) | PGDSLC22A6CACNA2D1CACNB3CACNA1C | |
| SCHEMBL3283254 | 0.74 | TDP1 (0.48) | PGDSLC22A6ADRA1ATDP1SMN1; SMN2 | |
| SCHEMBL26665097 | 0.72 | TSHR (0.35) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556061-B1 | Cement Admixture composition | GRACE W R & CO (US) | 1997-05-02 | — | — | EP | disclosed |
| US-5362323-A | Alkenyl ether maleic anhydride copolymers for slump loss | W. R. GRACE & CO. CONN. (US) | 1994-11-08 | — | — | US | disclosed |
| EP-0556061-A1 | Cement Admixture composition | W.R. Grace & Co.-Conn. (US) | 1993-08-18 | — | — | EP | disclosed |