Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058558 | 0.86 | MTNR1A (0.37) | MTNR1AMTNR1B | |
| SCHEMBL7057928 | 0.85 | MTNR1A (0.42) | MTNR1AMTNR1BGCGRTRPV1 | |
| SCHEMBL7057923 | 0.81 | MTNR1A (0.44) | MTNR1AMTNR1BGCGRTRPV1 | |
| SCHEMBL8822761 | 0.72 | MTNR1A (0.58) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7055218 | 0.72 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL7057717 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL8822694 | 0.69 | MTNR1A (0.39) | MTNR1AMTNR1B | |
| SCHEMBL7055536 | 0.68 | MTNR1A (0.48) | MTNR1AMTNR1B | |
| SCHEMBL7056605 | 0.68 | MTNR1A (0.37) | MTNR1AMTNR1B | |
| SCHEMBL7053413 | 0.66 | MTNR1A (0.35) | MTNR1AMTNR1BGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000069-A1 | MELATONIN AGONISTS FOR TREATING BENIGN PROSTATIC HYPERPLASIA | ELI LILLY AND COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |