Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 12/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.43 |
| ▸ | GABRP | O00591 | 8/20 | 0.43 |
| ▸ | GABRD | O14764 | 8/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.43 |
| ▸ | GABRE | P78334 | 8/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822774 | 0.94 | GABRA2 (0.44) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8822813 | 0.91 | GABRA2 (0.44) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL9027813 | 0.91 | GABRA2 (0.46) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8822757 | 0.90 | GABRA2 (0.43) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8822730 | 0.88 | GABRA2 (0.45) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8446011 | 0.88 | GABRA2 (0.44) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8822771 | 0.88 | GABRA2 (0.41) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8822785 | 0.87 | GABRA2 (0.44) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8446608 | 0.85 | GABRB3 (0.40) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8445349 | 0.84 | GABRB3 (0.39) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372982-B1 | Pyrrole insecticides | RHONE POULENC AGROCHIMIE (FR) | 1997-07-02 | — | — | EP | claimed |
| EP-0372982-A2 | Pyrrole insecticides | RHONE-POULENC AGROCHIMIE (FR) | 1990-06-13 | — | — | EP | claimed |
| EP-0372982-B1 | Pyrrole insecticides | RHONE POULENC AGROCHIMIE (FR) | 1997-07-02 | — | — | EP | disclosed |
| US-5506260-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | RHONE-POULENC AG COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| US-5187185-A | Pesticidal 1-arylpyrroles | RHONE-POULENC AG COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0372982-A2 | Pyrrole insecticides | RHONE-POULENC AGROCHIMIE (FR) | 1990-06-13 | — | — | EP | disclosed |