Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.45 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA9 | Q16790 | 9/20 | 0.44 |
| ▸ | CA12 | O43570 | 8/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622347 | 0.89 | PRKCA (0.57) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL8622350 | 0.89 | PRKCA (0.57) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL15061506 | 0.89 | TSHR (0.54) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL4178428 | 0.89 | TSHR (0.54) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL1527148 | 0.89 | TSHR (0.54) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL4178413 | 0.89 | TSHR (0.54) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL16328963 | 0.89 | TSHR (0.54) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL8700625 | 0.86 | PRKCA (0.54) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL8700630 | 0.86 | PRKCA (0.54) | PRKCAAKT1PTK2PAX8TSHR | |
| SCHEMBL10603093 | 0.85 | PRKCA (0.47) | PRKCAAKT1PTK2PAX8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014707-A1 | SIALYL Lex ANALOGUES AS INHIBITORS OF CELLULAR ADHESION | CYTEL CORPORATION (US) | 1997-04-24 | — | — | WO | disclosed |