Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.49 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 8/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.47 |
| ▸ | CA2 | P00918 | 8/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622350 | 1.00 | PRKCA (0.57) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL13435245 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL230378 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL2786496 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL7028051 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL16327524 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL13461633 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL230379 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL1527155 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 | |
| SCHEMBL7028056 | 0.94 | TSHR (0.54) | PRKCAAKT1PTK2TSHRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854218-A | Sialyl Lex analogues as inhibitors of cellular adhesion | CYTEL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5811404-A | INHIBIT CELLULAR ADHESION BETWEEN SELECTIN AND CELLS THAT EXPRESSES SIALYL LEWISX ON SURFACES | CYTEL CORPORATION (US) | 1998-09-22 | — | — | US | disclosed |
| US-5604207-A | INHIBIT SELECTIN MEDIATED CELLULAR ADHESION; TREATING INFLAMMATION, BLOOD CLOTTING | CYTEL CORPORATION (US) | 1997-02-18 | — | — | US | disclosed |
| WO-1994026760-A1 | SIALYL Lex ANALOGUES AS INHIBITORS OF CELLULAR ADHESION | CYTEL CORPORATION (US) | 1994-11-24 | — | — | WO | disclosed |