Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610596 | 0.93 | AR (0.71) | ARKCNH2SRD5A2 | |
| SCHEMBL7610600 | 0.93 | AR (0.71) | ARKCNH2SRD5A2 | |
| SCHEMBL7615525 | 0.85 | AR (0.69) | ARKCNH2SRD5A2 | |
| SCHEMBL7615518 | 0.85 | AR (0.69) | ARKCNH2SRD5A2 | |
| SCHEMBL5247649 | 0.84 | AR (0.74) | ARKCNH2SRD5A2 | |
| SCHEMBL13403347 | 0.84 | AR (0.74) | ARKCNH2SRD5A2 | |
| SCHEMBL5874196 | 0.84 | AR (0.74) | ARKCNH2SRD5A2 | |
| SCHEMBL9023095 | 0.84 | AR (0.57) | ARKCNH2SRD5A2 | |
| SCHEMBL7616774 | 0.83 | AR (0.67) | ARKCNH2SRD5A2 | |
| SCHEMBL7616766 | 0.83 | AR (0.67) | ARKCNH2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538192-B1 | New 17-beta-substituted aza-androstanderivatives | CIBA GEIGY AG (CH) | 1997-04-23 | — | — | EP | disclosed |
| EP-0538192-A1 | New 17-beta-substituted aza-androstanderivatives | CIBA-GEIGY AG (CH) | 1993-04-21 | — | — | EP | disclosed |