SCHEMBL9023095

CN1C(=O)C=C[C@]2(C)[C@H]3CC[C@]4(C)[C@@H](OC(=O)NC(c5ccccc5)c5ccccc5)CC[C@H]4[C@@H]3CC[C@@H]12

nearest known ligand 0.59

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	AR	P10275	8/20	0.57

▸	SRD5A2	P31213	1/20	0.53

▸	KCNH2	Q12809	5/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9022405	0.96	AR (0.53)	ARSRD5A2KCNH2
SCHEMBL9022408	0.86	AR (0.49)	ARSRD5A2KCNH2
SCHEMBL916871	0.85	AR (0.66)	ARSRD5A2KCNH2
SCHEMBL916870	0.85	AR (0.66)	ARSRD5A2KCNH2
SCHEMBL9023047	0.85	AR (0.66)	ARSRD5A2KCNH2
SCHEMBL9022687	0.84	AR (0.56)	ARSRD5A2KCNH2
SCHEMBL8823341	0.84	AR (0.70)	ARSRD5A2KCNH2
SCHEMBL9022536	0.83	SRD5A1 (0.61)	SRD5A2
SCHEMBL7610596	0.83	AR (0.71)	ARSRD5A2KCNH2
SCHEMBL7610600	0.83	AR (0.71)	ARSRD5A2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0484094-B1	Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use	SANKYO CO (JP)	1996-06-26	—	—	EP	claimed