Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.68 |
| ▸ | CTSS | P25774 | 10/20 | 0.68 |
| ▸ | CTSL | P07711 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823896 | 0.98 | CTSK (0.66) | CTSKCTSSCTSLCTSBPTPN1 | |
| SCHEMBL7139390 | 0.96 | CTSK (0.66) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5934709 | 0.86 | CTSK (0.76) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL8823904 | 0.86 | CTSK (0.65) | CTSKCTSSCTSLCTSBPTPN1 | |
| SCHEMBL7137945 | 0.84 | CTSL (0.63) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4669748 | 0.84 | CTSK (0.73) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5934588 | 0.84 | CTSK (0.63) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7169021 | 0.83 | CTSK (0.73) | CTSKCTSSCTSLCTSB | |
| SCHEMBL8823885 | 0.83 | CTSK (0.67) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL5934832 | 0.82 | CTSK (0.70) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | claimed |
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |