Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.65 |
| ▸ | CTSS | P25774 | 10/20 | 0.65 |
| ▸ | CTSL | P07711 | 5/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823885 | 0.98 | CTSK (0.67) | CTSKCTSSCTSLCTSBITGB3 | |
| SCHEMBL8823896 | 0.84 | CTSK (0.66) | CTSKCTSSCTSLCTSBPTPN1 | |
| SCHEMBL8823904 | 0.84 | CTSK (0.65) | CTSKCTSSCTSLCTSBPTPN1 | |
| SCHEMBL7164038 | 0.83 | CTSK (0.62) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL8823902 | 0.82 | CTSK (0.68) | CTSKCTSSCTSLCTSBPTPN1 | |
| SCHEMBL27575296 | 0.81 | CTSK (0.69) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL27575295 | 0.81 | CTSK (0.69) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7167212 | 0.81 | CTSK (0.69) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL7611750 | 0.80 | CTSK (0.67) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL8824069 | 0.79 | CTSK (0.66) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |