Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019175 | 0.93 | L3MBTL1 (0.61) | L3MBTL1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL2021875 | 0.93 | L3MBTL1 (0.61) | L3MBTL1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL5878404 | 0.93 | L3MBTL1 (0.61) | L3MBTL1LMNASMN1; SMN2MAPTHTT | |
| Hydrochloric Acid SCHEMBL4925995 | 0.91 | L3MBTL1 (0.64) | L3MBTL1LMNASMN1; SMN2MAPTHTT | |
| Hydrochloric Acid SCHEMBL6539516 | 0.91 | L3MBTL1 (0.64) | L3MBTL1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL772836 | 0.88 | HTR1D (0.52) | L3MBTL1SMN1; SMN2MAPTKMT2AKDM4E | |
| SCHEMBL11127254 | 0.87 | SMN1; SMN2 (0.61) | L3MBTL1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL772498 | 0.86 | KDM1A (0.56) | L3MBTL1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL8994531 | 0.84 | TSHR (0.56) | LTA4HL3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL1496800 | 0.84 | TSHR (0.56) | LTA4HL3MBTL1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | disclosed |