Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 8/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823892 | 0.84 | CTSK (0.69) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8824012 | 0.81 | CTSK (0.54) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL7764593 | 0.80 | CTSL (0.65) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL7315453 | 0.80 | CAPN1 (0.70) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL7315481 | 0.80 | CAPN1 (0.70) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8823924 | 0.79 | CTSK (0.53) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8823926 | 0.77 | CTSK (0.56) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8823932 | 0.77 | CTSK (0.53) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8823925 | 0.77 | CTSK (0.67) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8823929 | 0.77 | CTSK (0.67) | CTSKCAPN1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049668-A1 | INHIBITIORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-31 | — | — | WO | claimed |