Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664076 | 0.90 | PLG (0.56) | PLGF10PLAU | |
| Hydrochloric Acid SCHEMBL9710413 | 0.86 | F2 (0.53) | CA2F2ITGB3ITGA2BTMPRSS6 | |
| SCHEMBL4968238 | 0.86 | PLG (0.62) | F2PLGF10PLAUPRSS1 | |
| SCHEMBL9710936 | 0.84 | MME (0.51) | CA2F2MMEACECPA1 | |
| Hydrochloric Acid SCHEMBL9710928 | 0.84 | F2 (0.52) | F2ITGB3ITGA2BPLGF10 | |
| SCHEMBL3419348 | 0.83 | ITGB1 (0.51) | CA2F2ITGB3ITGA2BCA1 | |
| SCHEMBL9710389 | 0.83 | F2 (0.70) | F2ITGB3ITGA2BTMPRSS6PLG | |
| SCHEMBL3057528 | 0.82 | F2 (0.60) | CA2F2ITGB3ITGA2BTMPRSS6 | |
| SCHEMBL3419341 | 0.82 | F2 (0.60) | CA2F2ITGB3ITGA2BTMPRSS6 | |
| SCHEMBL9710517 | 0.82 | F2 (0.57) | CA2F2ITGB3ITGA2BTMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607937-A | Piperazides of substituted phenylalanine derivatives as thrombin inhibitors | PENTAPHARM AG (CH) | 1997-03-04 | — | — | US | disclosed |