Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | CPA1 | P15085 | 4/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823969 | 0.84 | CA2 (0.56) | MMEACECPA1ACE2CA2 | |
| SCHEMBL7300647 | 0.81 | MMP2 (0.61) | MMP2MMP9F2KAT6A | |
| SCHEMBL9710605 | 0.81 | MMP2 (0.61) | MMP2MMP9F2KAT6A | |
| SCHEMBL9710933 | 0.81 | CTSS (0.56) | MMEACECPA1ACE2CA2 | |
| SCHEMBL9710415 | 0.81 | CTSS (0.43) | F2CTSBCTSSCTSK | |
| SCHEMBL9710396 | 0.81 | CTSS (0.56) | MMEACECPA1ACE2CA2 | |
| SCHEMBL8954732 | 0.80 | CA2 (0.43) | MMEACECPA1ACE2CA2 | |
| SCHEMBL9664076 | 0.79 | PLG (0.56) | — | |
| SCHEMBL3089218 | 0.77 | KAT6A (0.51) | F2KAT6ACTSS | |
| SCHEMBL8954628 | 0.73 | F10 (0.50) | CA2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |