Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 4/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710389 | 0.88 | F2 (0.70) | F2ITGB3ITGA2BPLGTMPRSS6 | |
| SCHEMBL9257772 | 0.82 | MMP9 (0.73) | F2ITGB3ITGA2BMMP2MMP9 | |
| SCHEMBL3419341 | 0.82 | F2 (0.60) | F2ITGB3ITGA2BPLGTMPRSS6 | |
| SCHEMBL8823969 | 0.82 | CA2 (0.56) | F2ITGB3ITGA2BPLGTMPRSS6 | |
| SCHEMBL3057528 | 0.82 | F2 (0.60) | F2ITGB3ITGA2BPLGTMPRSS6 | |
| SCHEMBL8954940 | 0.81 | PLG (0.65) | PLGF10PLAU | |
| SCHEMBL8954699 | 0.78 | PLG (0.74) | F2PLGF10PLAU | |
| SCHEMBL9665995 | 0.78 | PLG (0.74) | F2PLGF10PLAU | |
| SCHEMBL9710523 | 0.78 | CA2 (0.50) | F2ITGB3ITGA2BPLGTMPRSS6 | |
| SCHEMBL18229018 | 0.77 | F2 (0.52) | F2CA2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |