Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061056 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10CYP11B1CYP11B2 | |
| SCHEMBL16956497 | 0.81 | NQO1 (0.46) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7144108 | 0.79 | HSD17B10 (0.51) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL26768678 | 0.79 | BAZ2B (0.56) | KDM4EALDH1A1HSD17B10CYP11B1CYP11B2 | |
| SCHEMBL7315568 | 0.78 | ADRA1A (0.44) | HSD17B10IDO1ADRA1ATAAR1HTR2A | |
| SCHEMBL7322443 | 0.78 | HSD17B10 (0.68) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30468420 | 0.78 | HSD17B10 (0.68) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7308036 | 0.78 | HSD17B10 (0.50) | KDM4EALDH1A1HSD17B10IDO1 | |
| SCHEMBL487944 | 0.78 | HSD17B10 (0.62) | HSD17B10IDO1ADRA1ATAAR1HTR2A | |
| SCHEMBL1638977 | 0.78 | GAA (0.52) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-5684130-A | Process for synthesis of organic compounds using magnetic particles | SOLID PHASE SCIENCES CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |