Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824849 | 0.89 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL8824734 | 0.88 | CYP2C19 (0.32) | LMNA | |
| SCHEMBL8144303 | 0.80 | CYP2C19 (0.52) | LMNASMN1; SMN2 | |
| SCHEMBL7131710 | 0.70 | LMNA (0.38) | LMNAL3MBTL1PDE4ASMN1; SMN2TDP1 | |
| SCHEMBL29335645 | 0.65 | LMNA (0.50) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Adonitol SCHEMBL29012527 | 0.63 | LMNA (0.62) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Iosimide SCHEMBL898150 | 0.63 | CA2 (0.33) | L3MBTL1 | |
| Xylitol SCHEMBL1924966 | 0.63 | LMNA (0.83) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Xylitol SCHEMBL5273838 | 0.63 | LMNA (0.83) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Xylitol SCHEMBL4599492 | 0.63 | LMNA (0.83) | LMNAL3MBTL1PDE4ATDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693311-A | Polyiodinated compounds, process for preparing them and diagnostic compositions | GUERBET S.A. (FR) | 1997-12-02 | — | — | US | disclosed |