Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15472453 | 0.80 | TSHR (0.39) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL14038948 | 0.80 | TSHR (0.39) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL806955 | 0.80 | TSHR (0.39) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL15472460 | 0.80 | TSHR (0.39) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL27934777 | 0.78 | TSHR (0.37) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL15998191 | 0.78 | TSHR (0.42) | TSHRLMNAALOX15 | |
| SCHEMBL5544727 | 0.78 | TSHR (0.37) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL15998219 | 0.77 | ALDH1A1 (0.42) | LMNAALOX15HCAR2 | |
| SCHEMBL882111 | 0.77 | — | — | |
| SCHEMBL12310621 | 0.77 | TSHR (0.36) | TSHRLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937350-A1 | 1' -substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2012039791-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012012776-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2012-01-26 | — | — | WO | disclosed |