SCHEMBL5544727

SCHEMBL5544727

CCOC(CC)C(=O)OC(C)C

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
LMNA P02545 4/20 0.35
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.32
ALOX15 P16050 2/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
THRB P10828 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30
PPARA Q07869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27769377 0.82 LMNA (0.33) TSHRLMNAALOX15HCAR2PPARA
SCHEMBL15472453 0.80 TSHR (0.39) TSHRLMNAALOX15HCAR2
SCHEMBL14038948 0.80 TSHR (0.39) TSHRLMNAALOX15HCAR2
SCHEMBL806955 0.80 TSHR (0.39) TSHRLMNAALOX15HCAR2
SCHEMBL15472460 0.80 TSHR (0.39) TSHRLMNAALOX15HCAR2
SCHEMBL249492 0.79 SOAT1 (0.40) TSHRLMNAALDH1A1HSD17B10ALOX15
SCHEMBL3284678 0.79 ALDH1A1 (0.43) LMNAALDH1A1HSD17B10ALOX15MGAM
SCHEMBL27748154 0.79 GABRP (0.44) TSHRLMNA
SCHEMBL882485 0.78 TSHR (0.37) TSHRLMNAALOX15HCAR2
SCHEMBL27934777 0.78 TSHR (0.37) TSHRLMNAALOX15HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732707-B1 ACTIVATION METHOD COMMW SCIENT IND RES ORG (AU) 2015-04-22 EP disclosed
US-8557343-B2 Activation method THE BOEING COMPANY (US) 2013-10-15 US disclosed
US-20070218295-A1 Activation Method COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2007-09-20 US disclosed