Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 18/20 | 0.60 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825095 | 1.00 | LTB4R (0.60) | LTB4RLTB4R2DRD3TLR7 | |
| SCHEMBL8825650 | 0.92 | LTB4R (0.57) | LTB4RLTB4R2DRD3TLR7 | |
| SCHEMBL8825656 | 0.92 | LTB4R (0.57) | LTB4RLTB4R2DRD3TLR7 | |
| SCHEMBL8825303 | 0.88 | LTB4R (0.67) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825307 | 0.88 | LTB4R (0.67) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825421 | 0.87 | LTB4R (0.46) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825422 | 0.87 | LTB4R (0.46) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825426 | 0.85 | LTB4R (0.58) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825429 | 0.85 | LTB4R (0.58) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825642 | 0.85 | LTB4R (0.47) | LTB4RLTB4R2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624943-A | Pyridine compounds which are useful as leukotriene-B4 -antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | claimed |
| EP-0651745-A1 | NEW PYRIDINE DERIVATIVES AS LEUKCOTRIENE B 4? ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-05-10 | — | — | EP | claimed |
| WO-1994002464-A1 | NEW PYRIDINE DERIVATIVES AS LEUKCOTRIENE B4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-03 | — | — | WO | claimed |
| US-5624943-A | Pyridine compounds which are useful as leukotriene-B4 -antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |