Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 17/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825650 | 1.00 | LTB4R (0.57) | LTB4RLTB4R2DRD3TLR7FFAR1 | |
| SCHEMBL8825095 | 0.92 | LTB4R (0.60) | LTB4RLTB4R2DRD3TLR7 | |
| SCHEMBL8825091 | 0.92 | LTB4R (0.60) | LTB4RLTB4R2DRD3TLR7 | |
| SCHEMBL8825642 | 0.89 | LTB4R (0.47) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825645 | 0.89 | LTB4R (0.47) | LTB4RLTB4R2DRD3 | |
| SCHEMBL8825307 | 0.88 | LTB4R (0.67) | LTB4RLTB4R2DRD3FFAR1PPARG | |
| SCHEMBL8825303 | 0.88 | LTB4R (0.67) | LTB4RLTB4R2DRD3FFAR1PPARG | |
| SCHEMBL8825429 | 0.86 | LTB4R (0.58) | LTB4RLTB4R2DRD3FFAR1PPARG | |
| SCHEMBL8825426 | 0.86 | LTB4R (0.58) | LTB4RLTB4R2DRD3FFAR1PPARG | |
| SCHEMBL8825182 | 0.85 | LTB4R (0.54) | LTB4RLTB4R2DRD3TLR7FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624943-A | Pyridine compounds which are useful as leukotriene-B4 -antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | claimed |