Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450 | 0.85 | IDO1 (0.44) | IDO1TSHRCA12CA1CA2 | |
| Water SCHEMBL28337532 | 0.83 | IDO1 (0.43) | IDO1TSHRCA12CA1CA2 | |
| SCHEMBL18970059 | 0.81 | TAAR1 (0.44) | IDO1AGXTTAAR1ABCC4LMNA | |
| SCHEMBL19403588 | 0.79 | TAAR1 (0.50) | IDO1AGXTTAAR1ABCC4LMNA | |
| SCHEMBL8825508 | 0.78 | TAAR1 (0.54) | IDO1AGXTTAAR1ABCC4LMNA | |
| Biphenyl SCHEMBL8131646 | 0.76 | ALDH1A1 (0.39) | IDO1AGXTTAAR1TSHRALDH1A1 | |
| SCHEMBL7024703 | 0.74 | TAAR1 (0.50) | IDO1AGXTTAAR1ABCC4LMNA | |
| SCHEMBL5452387 | 0.74 | TAAR1 (0.50) | IDO1AGXTTAAR1ABCC4LMNA | |
| Thiophene SCHEMBL27980591 | 0.74 | IDO1 (0.36) | IDO1TSHRALDH1A1RAB9ACA12 | |
| SCHEMBL975422 | 0.71 | IDO1 (0.48) | IDO1AGXTTAAR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693720-A | COMPOUND HAVING ORGANIC NON-PEPTIDE MOIETY LINKED TO SOLID SUPPORT THROUGH SULFIDE; PHOTOSENSITIVITY | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5502246-A | Solid-phase synthesis utilizing photochemical carbon-sulfur bond cleavage of thioethers | ELI LILLY AND COMPANY (US) | 1996-03-26 | — | — | US | disclosed |