Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.48 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806835 | 1.00 | ELANE (0.48) | ELANEFABP7FABP5MEN1KMT2A | |
| SCHEMBL14875217 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL18036888 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL2062622 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL10768544 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL10758551 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL6893609 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL9039878 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL10767245 | 0.85 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL10675931 | 0.85 | ELANE (0.48) | ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703243-A | Intermediates for pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-12-30 | — | — | US | disclosed |