Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826139 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL8496214 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL8496219 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL8496217 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL8826234 | 0.90 | AGER (0.47) | MEN1KMT2A | |
| SCHEMBL8497090 | 0.90 | AGER (0.47) | MEN1KMT2A | |
| SCHEMBL8826230 | 0.90 | AGER (0.47) | MEN1KMT2A | |
| SCHEMBL8497094 | 0.90 | AGER (0.47) | MEN1KMT2A | |
| SCHEMBL8492532 | 0.87 | NR3C1 (0.51) | — | |
| SCHEMBL8826152 | 0.87 | NR3C1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631401-A | Inhibitors of protein farnesyltransferase and squalene synthase | ABBOTT LABORATORIES (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1995021815-A1 | CYCLOBUTANE DERIVATIVES AND THEIR USE AS INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND SQUALENE SYNTHASE | ABBOTT LABORATORIES (US) | 1995-08-17 | — | — | WO | disclosed |