Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR39 | O43194 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440111 | 0.66 | MAPT (0.46) | — | |
| SCHEMBL899400 | 0.64 | ADORA2A (0.32) | — | |
| SCHEMBL12590817 | 0.56 | RAB9A (0.48) | HRH4MAP4K4 | |
| SCHEMBL7072307 | 0.55 | — | — | |
| SCHEMBL10187127 | 0.54 | HRH4 (0.56) | GPR39HRH4 | |
| SCHEMBL7071992 | 0.54 | PIK3CD (0.31) | — | |
| SCHEMBL13685177 | 0.54 | PTGER4 (0.40) | HRH4 | |
| SCHEMBL1774600 | 0.53 | HRH4 (0.66) | GPR39HRH4 | |
| SCHEMBL28182726 | 0.51 | CDK5 (0.36) | — | |
| SCHEMBL22854663 | 0.51 | PHF8 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0625158-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |