Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826276 | 0.85 | PNP (0.46) | SLC29A1 | |
| SCHEMBL9360335 | 0.85 | PNP (0.46) | SLC29A1 | |
| SCHEMBL8939241 | 0.83 | HIF1A (0.52) | HIF1ASLC29A1EGFRERBB2 | |
| SCHEMBL8826156 | 0.83 | SLC29A1 (0.65) | HIF1ASLC29A1 | |
| SCHEMBL5199003 | 0.81 | HIF1A (0.56) | HIF1AEGFRERBB2 | |
| SCHEMBL5198998 | 0.81 | HIF1A (0.56) | HIF1AEGFRERBB2 | |
| SCHEMBL8826350 | 0.80 | SLC29A1 (0.51) | HIF1ASLC29A1 | |
| SCHEMBL4745554 | 0.80 | EGFR (0.61) | HIF1ASLC29A1EGFRERBB2 | |
| SCHEMBL4745556 | 0.80 | EGFR (0.61) | HIF1ASLC29A1EGFRERBB2 | |
| SCHEMBL21133221 | 0.80 | EGFR (0.61) | HIF1ASLC29A1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |