Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.65 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826224 | 0.86 | MGMT (0.53) | SLC29A1ADORA2AADORA1ADORA3TP53 | |
| SCHEMBL8826261 | 0.83 | HIF1A (0.49) | SLC29A1HIF1A | |
| SCHEMBL8826256 | 0.82 | ADORA3 (0.66) | SLC29A1ADORA2AADORA1ADORA3TP53 | |
| SCHEMBL8939241 | 0.81 | HIF1A (0.52) | SLC29A1HIF1A | |
| SCHEMBL8826218 | 0.79 | LMNA (0.64) | SLC29A1 | |
| SCHEMBL7054042 | 0.79 | SLC29A1 (1.00) | SLC29A1HIF1ASTAT6ADORA2AADORA1 | |
| SCHEMBL7054035 | 0.79 | SLC29A1 (1.00) | SLC29A1HIF1ASTAT6ADORA2AADORA1 | |
| SCHEMBL5199003 | 0.79 | HIF1A (0.56) | HIF1A | |
| SCHEMBL5198998 | 0.79 | HIF1A (0.56) | HIF1A | |
| SCHEMBL4745554 | 0.78 | EGFR (0.61) | SLC29A1HIF1ASTAT6ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |