Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826179 | 0.86 | SLC29A1 (0.56) | SLC29A1HIF1AADORA3ADORA2AADORA1 | |
| SCHEMBL8939236 | 0.85 | TSHR (0.59) | SLC29A1HIF1AADORA3ADORA2AADORA1 | |
| SCHEMBL8826529 | 0.85 | PGK1 (0.50) | ADORA3ADORA1 | |
| SCHEMBL9360359 | 0.85 | ADORA3 (0.57) | SLC29A1HIF1AADORA3 | |
| SCHEMBL8826176 | 0.85 | ADORA3 (0.57) | SLC29A1HIF1AADORA3 | |
| SCHEMBL8826256 | 0.83 | ADORA3 (0.66) | SLC29A1ADORA3ADORA2AADORA1 | |
| SCHEMBL9359951 | 0.82 | SLC29A1 (0.65) | SLC29A1HIF1AADORA3ADORA2AADORA1 | |
| SCHEMBL8826244 | 0.82 | SLC29A1 (0.65) | SLC29A1HIF1AADORA3ADORA2AADORA1 | |
| SCHEMBL9587631 | 0.81 | ALDH1A1 (0.54) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL9589274 | 0.81 | ALDH1A1 (0.54) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663154-A | VIRICIDES, HIV, HEPATITIS | GLAXO WELLCOME INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1993014103-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |