Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 10/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 10/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882856 | 0.87 | CYP4F2 (0.45) | CYP4F2CYP4A11KDM4EMEN1MAPT | |
| SCHEMBL798335 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1MAPTKMT2A | |
| SCHEMBL798312 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1MAPTKMT2A | |
| SCHEMBL798228 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1MAPTKMT2A | |
| SCHEMBL797992 | 0.78 | TBXAS1 (0.45) | CYP4F2CYP4A11TBXAS1 | |
| SCHEMBL798200 | 0.78 | TBXAS1 (0.45) | CYP4F2CYP4A11TBXAS1 | |
| SCHEMBL798204 | 0.78 | TBXAS1 (0.45) | CYP4F2CYP4A11TBXAS1 | |
| SCHEMBL798344 | 0.78 | TBXAS1 (0.45) | CYP4F2CYP4A11TBXAS1 | |
| SCHEMBL23533401 | 0.76 | GPR84 (0.43) | CYP4F2CYP4A11TBXAS1TSHRMEN1 | |
| SCHEMBL11292271 | 0.76 | GPR84 (0.43) | CYP4F2CYP4A11TBXAS1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040177-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA | KAREUS THERAPEUTICS, SA (CH) | 2012-03-29 | — | — | WO | disclosed |