Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827616 | 0.84 | HDAC1 (0.43) | AVPR2HDAC1HDAC6AVPR1AMEN1 | |
| SCHEMBL8827667 | 0.84 | LMNA (0.43) | AVPR2HDAC1HDAC6AVPR1AMEN1 | |
| SCHEMBL8827639 | 0.83 | AVPR2 (0.65) | AVPR2HDAC1HDAC6AVPR1AALDH1A1 | |
| SCHEMBL8827571 | 0.82 | AVPR1A (0.41) | AVPR2HDAC1HDAC6AVPR1AMEN1 | |
| SCHEMBL8827659 | 0.79 | AVPR2 (0.38) | AVPR2HDAC1HDAC6AVPR1AMEN1 | |
| SCHEMBL30824934 | 0.75 | AVPR2 (0.70) | AVPR2HDAC1HDAC6AVPR1AALDH1A1 | |
| SCHEMBL8827653 | 0.74 | AVPR2 (0.33) | AVPR2HDAC1HDAC6AVPR1AMEN1 | |
| SCHEMBL8827601 | 0.74 | AVPR2 (0.36) | AVPR2HDAC1HDAC6AVPR1AMEN1 | |
| SCHEMBL8827637 | 0.74 | PTGDR (0.39) | AVPR2HDAC1HDAC6AVPR1AMEN1 | |
| SCHEMBL7240942 | 0.73 | AVPR2 (0.69) | AVPR2HDAC1HDAC6AVPR1AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677299-A | VASOPRESSIN OR OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5498609-A | Benzoazepinyl compounds as oxytocin and vasopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0612319-A1 | BENZOHETEROCYCLIC COMPOUNDS AS OXYTOCIN AND VASOPRESSIN ANTAGONISTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |
| WO-1994004525-A1 | BENZOHETEROCYCLIC COMPOUNDS AS OXYTOCIN AND VASOPRESSIN ANTAGONISTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-03-03 | — | — | WO | disclosed |